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TESTODEPO EURO GENERICS
Active ingredients:Testosterone Enanthate Pharmacological category:Anabolic Steroid Composition:Every 1 ml contains 250 mg of Testosterone Enanthate in Ethyl oleate Mechanism of medicine action: Testosterone is the primary endogenous androgen. In their active form, all drugs in the class have a 17-beta-hydroxy group. Esterification of the 17-beta-hydroxy group produces com- pounds (Testosterone Enanthate and testosterone propionate) which have a longer duration of action and are hydrolyzed in vivo to free testosterone. Androgens are steroids that develop and maintain primary and secondary male sex characteristics. The effects of testosterone in humans and other vertebrates occur by way of two main mechanisms: by activation of the androgen receptor /directly or as DHT/, and by conversion to estradiol and activation of certain estrogen receptors. Free testosterone is transported into cytoplasm of target tissue cells, where it can bind to the androgen receptor, or can be reduced to 5-a di-hydrotestosterone by the cytoplasmic enzyme 5-alpha reductase. DHT binds to the same androgen receptor even more strongly than testosterone, so that its androgenic potency is about 5 times that of free testosterone. DHT-receptor complex under goes a structural change that allows it to move into the cell nucleus and bind directly to specific nucleotide sequences of the chromosomal DNA. The areas of binding are called hormone response elements, and influence transcriptional activity of certain genes, producing the androgen effects. Androgen receptors occur in many different vertebrate body system tissues, and both males and females respond similarly to similar levels. Greatly differing amounts of testosterone prenatally, at puberty, and throughout life account for a share of biological differences between males and females. Indications: Males: Testosterone Enanthate is indicated for replacement therapy in conditions associated with a deficiency or absence of endrogenous testosterone: Primary hypogonadism testicular failure due to cryptorchidism, bilateral torsion orchitis, vanishing testis syndrome, or orchidectomy. Hypogonadotropic hypogonadism idiopathic gonadotropin or LHRH deficiency, or pituitary-hypothalamic injury from tumors, trauma, or radiation. Testosterone Enanthate may be used to stimulate puberty in carefully selected males with clearly delayed puberty that is not secondary to a pathologic disorder. Females: Testosterone Enanthate may be used secondarily in women with advancing inoperable metastatic mammary cancer who are 1 to 5 years postmenopausal. Primary goals of therapy in these women include ablation of the ovaries. This treatment has also been used in premenopausal

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